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SUMMARY:Mechanorheology of cells and tissues: From quantitative method dev
 elopment to factors shaping the mechanical phenotype
DTSTART:20260924T090000Z
DTEND:20260924T100000Z
DTSTAMP:20261030T130400Z
UID:indico-event-1665@indico.ifj.edu.pl
DESCRIPTION:Speakers: Joanna Zemła (IFJ PAN)\n\nQuantitative methods for 
 characterizing the mechanical and viscoelastic properties of cells and tis
 sues are developed and applied across multiple biological systems. Cells a
 nd tissues are treated as heterogeneous viscoelastic materials whose respo
 nse depends on deformation amplitude\, excitation frequency\, and observat
 ion time. AFM force spectroscopy\, oscillatory AFM microrheology\, stress-
 relaxation measurements\, and macroscopic rheometry reveal mechanical chan
 ges associated with disease\, therapeutic response\, cytoskeletal reorgani
 zation\, and the cellular microenvironment. The results demonstrate that a
  complete mechanical phenotype requires parameters describing not only res
 istance to deformation but also viscous dissipation and time-dependent rel
 axation.\n\nhttps://indico.ifj.edu.pl/event/1665/
URL:https://indico.ifj.edu.pl/event/1665/
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